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Daniel Grenier

daniel grenier

Professeur titulaire
Discipline : microbiologie buccale, maladies parodontales, contrôle de l’infection

Pavillon de médecine dentaire, local 1752
418 656-2131, poste 7341
daniel.grenier@greb.ulaval.ca

Formation universitaire

Post-doctorat en biologie buccale, Université de Colombie-Britannique1988
Doctorat en microbiologie, Université Laval1986
Maîtrise en microbiologie, Université Laval1982
Baccalauréat en microbiologie, Université Laval1981

Secteurs d’activités

Facteurs de virulence des bactéries associées aux maladies parodontales.
Protéases de Porphyromonas gingivalis: facteurs de virulence et cibles thérapeutiques.
Interactions hôte-pathogène lors d’infections buccales.
Polyphénols de plantes et petits fruits: effets antimicrobiens, anti-protéases et anti-inflammatoires.
Mécanismes de pathogénicité du pathogène porcin Streptococcus suis.
Utilisation de bactériocines comme alternative aux antibiotiques pour les infections chez le porc.


Publications récentes (5 dernières années)

  1. Grenier D. Research report prepared for SEVENTH GENERATION INC. Antimicrobial activities of essential oils. Mai 2015, 12 pages.
  2. Jacques M, D Grenier, J Labrie, C Provost, CA Gagnon. 2015. Persistence of porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 in bacterial biofilms. J. Swine Hlth Prod. 23: 132-136.
  3. Lombardo Bedran TB, DP Spolidorio, D Grenier. 2015. Green tea polyphenol epigallocatechin-3-gallate and cranberry proanthocyanidins act in synergy with cathelicidin (LL-37) to reduce the LPS-induced inflammatory response in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts. Archs Oral Biol. 60: 845-853.
  4. Azelmat J, S Fiorito, S Genovese, F Epifano, D Grenier. 2013. Antimicrobial and anti-Inflammatory activities of Ppc-1, active principle of the cellular slime mold Polysphondylium pseudo-candidum. Med. Chem. In press.
  5. Vaillancourt K, G LeBel, M Frenette, M Gottschalk, D Grenier. Suicin 3908, a new lantibiotic produced by a strain of Streptococcus suis serotype 2 isolated from a healthy carrier pig. PLoS One 10(2):e0117245
  6. Atanassov C, L Bonifait, M Perivier, M Gottschalk, D Grenier. 2015. Candidate proteomic biomarkers for three genogroups of the swine pathogen Streptococcus suis serotype 2. BMC Microbiol. 15:84.
  7. Morin MP, TB Lombardo Bedran , J Fournier-Larente, B Haas, J Azelmat, D Grenier. 2015. Green tea extract and its major constituent epigallocatechin-3-gallate inhibit growth and halitosis-related properties of Solobacterium moorei. BMC Complement. Alt. Med. 15:48.
  8. Azelmat J, J Fournier-Larente, D Grenier. 2015. The anthraquinone rhein attenuates virulence gene expression in Porphyromonas gingivalis and exhibits synergistic antibacterial activity in association with metronidazole or natural compounds. Archs Oral Biol. 60:342-346.
  9. Yoshida K, M Yoshioka, H Okamura, S Moriyama, K Kawazoe, D Grenier, D Hinode. 2014. Preventive effect of Daiokanzoto (TJ-84) on 5-fluorouracil-induced human gingival cell death through the inhibition of reactive oxygen species production and NLRP3 inflammasome activation. PLoS One 9(11):e112689.
  10. Grenier D. Research report prepared for COLGATE-PALMOLIVE COMPANY. Studies on the anti-inflammatory properties of natural compounds using a co-culture model of human gingival fibroblasts and macrophages. Octobre 2014, 39 pages.
  11. LeBel G, K Vaillancourt, M Frenette, M Gottschalk, D Grenier. 2014. Suicin 90-1330 from a non-virulent strain of Streptococcus suis: a nisin-related lantibiotic active on Gram-positive swine pathogens. Appl. Environ. Microbiol. 80: 5484-5492.
  12. Lombardo Bedran TB, MP Mayer, DP Spolidorio, D Grenier. 2014. Synergistic anti-inflammatory activity of the antimicrobial peptides human beta-defensin-3 (hBD-3) and cathelicidin (LL-37) in a three-dimensional co-culture model of gingival epithelial cells and fibroblasts. PLoS One 9(9):e106766.
  13. Segura M, H Zheng, AD Greeff, GF Gao, D Grenier, Y Jiang, C Lu, D Maskell, K Oishi, M Okura, R Osawa, C Schultsz, C Schwerk, T Sekizaki, H Smith, P Srimanote, D Takamatsu, J Tang, T Tenenbaum, P Tharavichitkul, NT Hoa, P Valentin-Weigand, JM Wells, H Wertheim, B Zhu, M Gottschalk, J Xu. 2014. Latest developments on Streptococcus suis: an emerging zoonotic pathogen: part 1. Future Microbiol. 9: 441-444.
  14. Segura M, H Zheng, AD Greeff, GF Gao, D Grenier, Y Jiang, C Lu, D Maskell, K Oishi, M Okura, R Osawa, C Schultsz, C Schwerk, T Sekizaki, H Smith, P Srimanote, D Takamatsu, J Tang, T Tenenbaum, P Tharavichitkul, NT Hoa, P Valentin-Weigand, JM Wells, H Wertheim, B Zhu, M Gottschalk, J Xu. 2014. Latest developments on Streptococcus suis: an emerging zoonotic pathogen: part 2. Future Microbiol. 9: 587-591.
  15. Liao J, J Azelmat, L Zhao, M Yoshioka, D Hinode, D Grenier. 2014. The Kampo medicine Rokumigan possesses antibiofilm, anti-inflammatory and wound healing properties. BioMed Res. Int. 2014:436206.
  16. Haas B, L Bonifait, K Vaillancourt, SJ Charette, M Gottschalk, D Grenier. 2014. Characterization of DNase activity and gene in Streptococcus suis and evidence for a role as virulence factor. BMC Res. Notes 7:424.
  17. Marttila E, A Järvensivu, T Sorsa, D Grenier, M Richardson, K Kari, T Tervahartiala, R Rautemaa. 2014. Intracellular localization of Treponema denticola chymotrypsin-like proteinase in chronic periodontitis. J. Oral Microbiol. 6.doi:10.3402/jom.v6.24349.
  18. Dang Y, C Lachance, Y Wang, CA Gagnon, C Savard, M Segura, D Grenier, M Gottschalk. 2014. Transcriptional approach to study porcine tracheal epithelial cells individually or dually infected with swine influenza virus and Streptococcus suis. BMC Vet. Res. 10:86.
  19. Bonifait L, M Veillette, V Létourneau, D Grenier, C Duchaine. 2014. Detection of Streptococcus suis in bioaerosols of swine confinement buildings. Appl. Environ. Microbiol. 80: 3296-3304.
  20. Tanabe SI, M Yoshioka, D Hinode, D Grenier. 2014. Subinhibitory concentration of tetracyclines induce LPS shedding by Porphyromonas gingivalis and modulate host inflammatory response. J. Periodontal Res. 49: 603-608.
  21. Villinski JR, C Bergeron, JC Cannistra, JB Gloer, CM Coleman, D Ferreira, J Azelmat, D Grenier, S Gafner. 2014. Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis. J. Nat. Prod. 77: 521-526.
  22. Lombardo Bedran T, L Grignon, D Spolidorio, L Zhao, D Grenier. 2014. Subinhibitory concentrations of triclosan promote S. mutans biofilm formation and adherence to epithelial cells. PloS One 9:e89059.
  23. Lombardo Bedran T, K Feghali, L Zhao, D Spolidorio, D Grenier. 2014. Green tea extract and its major constituent epigallocatechin-3-gallate induce epithelial β-defensin secretion and prevent β-defensin degradation by Porphyromonas gingivalis. J. Periodontal Res. 49: 615-623.
  24. Amou T, D Hinode, M Yoshioka, D Grenier. 2014. Relationship between halitosis and periodontal disease-associated oral bacteria in tongue coatings. Int. J. Dent. Hygiene. 12: 145-151.
  25. Bonifait L, L Zhao, J Azelmat, S Genovese, F Epifano, D Grenier. 2013. Synthesis and biological activities of 2,6-dihydroxy-4-isopentenyloxychalcone as an antimicrobial and anti-Inflammatory compound. Med. Chem. 10:300-303.
  26. LeBel G, F Piché, M Frenette, M Gottschalk, D Grenier. 2013. Antimicrobial activity of nisin against the swine pathogen Streptococcus suis and synergistic interaction with antibiotics. Peptides 50: 19-23.
  27. Grenier D. 2013. Binding properties of Treponema denticola lipooligosaccharide. J. Oral Microbiol. doi: 10.3402/JOM.v5i0.21517.
  28. Lombardo Bedran T, J Azelmat, D Spolidorio, D Grenier. 2013. Fibrinogen-induced Streptococcus mutans biofilm formation and adherence to endothelial cells. BioMed Res. Int. 2013:431465.
  29. La VD, L Zhao, F Epifano, S Genovese, D Grenier. 2013. Anti-inflammatory and wound healing potential of Citrus auraptene. J. Med. Food. 16: 961-964.
  30. Liao J, L Zhao, M Yoshioka, D Hinode, D Grenier. 2013. Effects of Japanese traditional herbal medicines (Kampo) on growth and virulence properties of Porphyromonas gingivalis and viability of oral epithelial cells. Pharm. Biol. 51: 1538-1544.
  31. Zhao L, A Marquis, VD La, M Agamennone, F Loiodice, P Tortorella, D Grenier. 2013. Effects of biphenyl sulfonylamino methyl bisphosphonic acids on Porphyromonas gingivalis and cytokine secretion by oral epithelial cells. Med. Chem. 9: 855-860.
  32. Vaillancourt K, L Bonifait, L Grignon, M Frenette, M Gottschalk, D Grenier. 2013. Identification and characterization of a new cell surface protein possessing factor H-binding activity in the swine pathogen and zoonotic agent Streptococcus suis. J. Med. Microbiol. 62: 1073-1080.
  33. Zhao L, VD La, D Grenier. 2013. Antibacterial, anti-adherence, anti-protease, and anti-inflammatory properties of tea extracts: Potential benefits for periodontal diseases. J. Med. Food. 16: 428-436.
  34. Santos J, A Marquis, F Epifano, S Genovese, M Curini, D Grenier. 2013. Collinin reduces Porphyromonas gingivalis growth and collagenase activity and inhibits the LPS-induced macrophage inflammatory response and osteoclast differentiation and function. J. Periodontol. 84: 704-711.
  35. Grenier D. 2013. Porphyromonas gingivalis outer membrane vesicles mediate coaggregation and piggybacking of Treponema denticola and Lachnoanaerobaculum saburreum. Int. J. Dent. 2013:305476.
  36. Gottschalk M, S Lacouture, L Bonifait, D Roy, N Fittipaldi, D Grenier. 2013. Characterization of Streptococcus suis isolates recovered between 2008 and 2011 from diseased pigs in Quebec, Canada. Vet. Microbiol. 162: 819-825.
  37. Tanabe SI, D Grenier. 2012. Characterization of volatile sulfur compounds production by Solobacterium moorei. Arch. Oral Biol. 57: 1639-1643.
  38. Boyle B, K Vaillancourt, L Bonifait, SJ Charette, M Gottschalk, D Grenier. 2012. Genome sequence of the swine pathogen S. suis serotype 2 strain S735. J. Bacteriol. 194: 6343-6344.
  39. Grenier D. Research report prepared for TOM’S OF MAINE. Antimicrobial activities of plant extracts. Décembre 2012, 26 pages.Marquis A, S Genovese, F Epifano, D Grenier. 2012. The plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease. BMC Complement. Altern. Med. 12:80.
  40. Feghali K, D Grenier. 2012. Priming effect of fibronectin fragments on the macrophage inflammatory response: Potential contribution to periodontitis. Inflammation 35: 1696-1705.
  41. Bonifait L, A Marquis, S Genovese, F Epifano, D Grenier. 2012. Synthesis and antimicrobial activity of geranyloxy- and farnesyloxy-acetophenone derivatives against oral pathogens. Fitoterapia 83: 996-999.
  42. Feghali K, M Feldman, VD La, J Santos, D Grenier. 2012. Cranberry proanthocyanidins: Natural weapons against periodontal diseases. J. Agric. Food Chem. 60: 5728-5735.
  43. Desjardins J, SI Tanabe, C Bergeron, S Gafner, D Grenier. 2012. Anthocyanin-rich black currant extract and cyanidin-3-O-glucoside have cytoprotective and anti-inflammatory properties. J. Med. Food 15: 1045-1050.
  44. Feldman M, D Grenier. 2012. Cranberry proanthocyanidins act in synergy with licochalcone A to reduce Porphyromonas gingivalis growth and virulence properties, and to suppress cytokine secretion by macrophages. J. Appl. Microbiol. 113: 438-447.
  45. Feldman M, S Tanabe, A Howell, D Grenier. 2012. Cranberry proanthocyanidins inhibit the adherence properties of Candida albicans and cytokine secretion by oral epithelial cells. BMC Complement. Altern. Med. 12:6.
  46. Fittipaldi N, M Segura, D Grenier, M Gottschalk. 2012. Virulence factors involved in the pathogenesis of the infection caused by the swine pathogen and zoonotic agent Streptococcus suis. Future Microbiol. 7: 259-279.
  47. Lombardo Bedran TB, RAC Marcantonio, R Spin Neto, MP Alves Mayer, D Grenier, LC Spolidorio, D Palomari Spolidorio. 2012. Porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study. J. Oral Microbiol. doi: 10.3402/jom.v4i0.10123.
  48. Tanabe SI, J Desjardins, C Bergeron, S Gafner, JR Villinski, D Grenier. 2012. Reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan A from licorice. J. Breath Res. 6(1):016006.
  49. Messier C, F Epifano, S Genovese, D Grenier. 2012. Licorice and its potential beneficial effects in common oro-dental diseases. Oral Dis. 18: 32-39.
  50. Gafner S, C Bergeron, JR Villinski, M Godejohann, P Kessler, JH Cardellina, D Ferreira, K Feghali, D Grenier. 2011. Isoflavonoids and coumarins from Glycyrrhiza uralensis: Antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification. J. Nat. Prod. 74: 2514-2519.
  51. Desjardins J, D Grenier. 2011. Neutralizing effect of green tea epigallocatechin-3-gallate on nicotine-induced toxicity and chemokine (C-C motif) ligand 5 secretion by human oral epithelial cells and fibroblasts. J. Invest. Clin. Dent. 3: 189-197.
  52. Feldman M, VD La, TB Lombardo Bedran, D Palomari Spolidorio, D Grenier. 2011. Porphyromonas gingivalis-mediated shedding of extracellular matrix metalloproteinase inducer (EMMPRIN) by oral epithelial cells: a potential role in inflammatory periodontal disease. Microbes Infect. 13: 1261-1269.
  53. La VD, S Tanabe, C Bergeron, S Gafner, D Grenier. 2011. Modulation of matrix metalloproteinase and cytokine production by licorice isolates licoricidin and licorisoflavan A: a potential therapeutic approach for periodontitis. J. Periodontol. 82: 122-128.
  54. Mahtout H, F Chandad, JM Rojo, D Grenier. 2011. Fusobacterium nucleatum binding to complement regulatory protein CD46 modulates the expression and secretion of cytokines and matrix metalloproteinases by oral epithelial cells. J. Periodontol. 82: 311-319.
  55. Bonifait L, D Grenier. 2011. The SspA subtilisin protease of Streptococcus suis triggers a pro-inflammatory response in macrophages through non-proteolytic mechanism. BMC Microbiol. 11: 47.
  56. Feldman M, S Tanabe, F Epifano, S Genevese, M Curini, D Grenier. 2011. Antibacterial and anti-inflammatory activities of 4-hydroxycordoin: potential therapeutic benefits. J. Nat. Prod. 74: 26-31.
  57. Messier C, F Epifano, S Genovese, D Grenier. 2011. Inhibition of Candida albicans biofilm formation and yeast-hyphal transition by 4-hydroxycordoin. Phytomedicine 18: 380-383.
  58. Bonifait L, K Vaillancourt, M Gottschalk, M Frenette, D Grenier. 2011. Purification and characterization of the subtilisin-like protease of Streptococcus suis that contributes to its virulence. Vet. Microbiol. 148: 333-340.
  59. Grenier D, VD La. 2011. Proteases of Porphyromonas gingivalis as important virulence factors in periodontal disease and potential targets for plant-derived compounds. Curr. Drug Targets 12: 322-331.
  60. Feghali K, S Tanabe, D Grenier. 2011. Soluble CD14 induces cytokine release by human oral epithelial cells. J. Periodontal Res. 46: 147-152.
  61. Mahtout H, S Curt, F Chandad, M Rouabhia, D Grenier. 2011. Effect of periodontopathogen lipopolysaccharides and proinflammatory cytokines on CD46, CD55, and CD59 gene/protein expression by oral epithelial cells. FEMS Immunol. Med. Microbiol. 62: 295-303.
  62. Santos J, VD La, C Bergeron, D Grenier. 2011. Inhibition of host- and bacteria-derived proteinases by natural anthocyanins. J. Periodontal Res. 46: 550-557.
  63. Tanabe S, J Santos, VD La, AB Howell, D Grenier. 2011. Cranberry proanthocyanidins inhibit the RANKL-dependent differentiation and function of human osteoclasts. Molecules 16: 2365-2374.
  64. Grenier D, SI Tanabe. 2011. Transferrin as a source of iron for Campylobacter rectus. J. Oral Microbiol. doi:10.3402/jom.v3i0.5660.
  65. Bonifait L, SJ Charette, G Filion, M Gottschalk, D Grenier. 2011. Amoeba host model for evaluation of Streptococcus suis virulence. Appl. Environ. Microbiol. 77: 6271-6273.
  66. Messier C, D Grenier. 2011. Effect of licorice compounds licochalcone A, glabridin and glycyrrhizic acid on growth and virulence properties of Candida albicans. Mycoses 54(6):e801-6.
  67. Feldman M, J Santos, D Grenier. 2011. Comparative evaluation of two structurally related flavonoids, isoliquiritigenin and liquiritigenin, for their oral infection therapeutic potential. J. Nat. Prod. 74: 1862-1867.
  68. Grenier D, J Cazalis, G Gagnon. 2011. Response of periodontitis and healthy patients in a Porphyromonas gingivalis-stimulated whole-blood model. J. Invest. Clin. Dent. 2: 38-42.

Conférences et communications scientifiques récentes (5 dernières années)

  1. Grenier D. Mieux connaître et gérer les risques de transmission d’infection. en cabinet dentaire. Société dentaire de Québec, Québec (Canada), Mars 2015.
  2. Haas B, D Grenier. Characterization of membrane vesicles produced by the swine pathogen Streptococcus suis. 115th General Meeting of the American Society for Microbiology, New Orleans (USA), Juin 2015.
  3. Haas B, D Grenier. Effect of sub-inhibitory concentrations of antibiotics on virulence factor gene expression by and pro-inflammatory potential of Streptococcus suis. 8ième Symposium du Centre de recherche en infectiologie porcine, St-Hyacinthe (Canada), Mai 2015.
  4. Lebel G, K Vaillancourt, F Piché, O Jerczynski, S Lacouture, M Frenette, M Gottschalk, D Grenier. Isolement et identification de bactéries indigènes du porc productrices de bactériocines actives contre d’importants pathogènes porcins. 8ième Symposium du Centre de recherche en infectiologie porcine, St-Hyacinthe (Canada), Mai 2015.
  5. Roy D, D Grenier, M Segura, A Mathieu-Denoncourt, M Gottschalk. Recruitment of human factor H at the bacterial surface: a possible role in the pathogenesis of the infection caused by Streptococcus suis. 8ième Symposium du Centre de recherche en infectiologie porcine, St-Hyacinthe (Canada), Mai 2015.
  6. Chuzeville S, JP Auger, D Grenier, M Gottschalk. The challenge of identifying universal virulence factors of Streptococcus suis serotype 2: the example of the di-peptidyl peptidase IV. 8ième Symposium du Centre de recherche en infectiologie porcine, St-Hyacinthe (Canada), Mai 2015.
  7. Grenier D. Les polyphénols de la canneberges : des molécules naturelles prometteuses pour la santé parodontale. Association des producteurs de canneberges du Québec. Québec (Canada), Mars 2015.
  8. Gauthier-Levesque L, L Bonifait, P Perrott, N Turgeon, D Grenier, C Duchaine. L’aérosolisation préférentielle de différentes souches de Streptococcus suis. 7ième Symposium du Centre de recherche en infectiologie porcine et avicole, Saint-Hyacinthe (Canada), Juin 2014.
  9. LeBel G, K Vaillancourt, M Frenette, M Gottschalk, D Grenier. Identification, purification and characterization of suicin 90-1330 produced by a non-virulent strain of Streptococcus suis. 4th International symposium on antimicrobial peptides, Lorient (France), Juin 2014.
  10. LeBel G, K Vaillancourt, M Frenette, M Gottschalk, D Grenier. Caractérisation d’une bactériocine de type lantibiotique produite par une souche non-virulente de Streptococcus suis. 7ième Symposium du Centre de recherche en infectiologie porcine et avicole, Saint-Hyacinthe (Canada), Juin 2014.
  11. Jacques M, CA Gagnon, D Grenier. Rôle des biofilms bactériens dans la persistence de virus pathogènes du porc dans l’environnement de la ferme. 7ième Symposium du Centre de recherche en infectiologie porcine et avicole, Saint-Hyacinthe (Canada), Juin 2014.
  12. Haas B, D Grenier. Isolation and characterization of microvesicles produced by the swine pathogens Streptococcus suis. 7ième Symposium du Centre de recherche en infectiologie porcine et avicole, Saint-Hyacinthe (Canada), Juin 2014.
  13. Grenier D. Les polyphénols: une arme naturelle prometteuse pour le contrôle des maladies parodontales. Colloque du Centre québécois de valorisation des biotechnologies, Québec (Canada), Novembre 2013.
  14. Bonifait L, M Veillette, D Grenier, C Duchaine. Ubiquity and persistence of Streptococcus suis bioaerosols in swine confinement buildings. 32nd Annual Conference American Association for Aerosol Research, Portland (USA), Octobre 2013.
  15. Grenier D. Bacteriocins as potential new weapons against Streptococcus suis infections. 1st International Workshop on Streptococcus suis, Beijing (China), Août 2013.
  16. Fiorito S, S Genovese, F Epifano, J Azelmat, D Grenier. Sintesi ed attività anti-batterica di cumarine ossiprenilate. XIII Congresso della Società Italiana di Fitochimica, Gargnano (Italy), Mai 2013.
  17. LeBel G, M Frenette, M Gottschalk, D Grenier. La nisine: un agent antibactérien prometteur pour le traitement des infections à Streptococcus suis?. Association Francophone pour le Savoir et 6e Symposium du Centre de Recherche en Infectiologie Porcine et Avicole, Québec (Canada), Mai 2013
  18. Haas B, K Vaillancourt, L Bonifait, D Grenier. Further characterization of Streptococcus suis serotype 2 hyaluronidase and a possible role in modulating bacterial adherence. Association Francophone pour le Savoir et 6e Symposium du Centre de Recherche en Infectiologie Porcine et Avicole, Québec (Canada), Mai 2013.
  19. Bonifait L, M Veillette, D Grenier, SJ Charrette, C Duchaine. Risk exposure of pig farmers to Streptococcus suis. 11th Conference of the Canadian Rural Health Research Society, Lévis (Canada), Octobre 2012.
  20. Bonifait L, M Veillette, D Grenier, SJ Charrette, C Duchaine. L’exposition à Streptococcus suis en milieu agricole. Congrès Québécois de Recherche en Santé Respiratoire, Montréal (Canada), Novembre 2012.
  21. Scaffa P, N Barros, C Vidal, IL Tersariol, D Pashley, J Santos, D Grenier, L Breschi, F Nascimento, M Carrilho. Cranberry proanthocyanidins inhibit cysteine cathepsin activity. International Association for Dental Research, Iguaçu Falls (Brazil), Juin 2012.
  22. Villinski JR, C Bergeron, M Dobrovolny, B Stewart, M Williams, C Schneider, SI Tanabe, J Desjardins, D Grenier, S Gafner. Glycyrrhiza uralensis containing toothpaste: Characterization of the extract and reduction of oral malodour in a clinical study. 8th Joint Meeting of AFERP, ASP, GA, PSE & SIF, New York (USA), Juillet 2012.
  23. Epifano F, S Genovese, L Zhao, VD La, D Grenier. In vitro anti-inflammatory and wound healing activities of Citrus auraptene. 8th Joint Meeting of AFERP, ASP, GA, PSE & SIF, New York (USA), Juillet 2012.
  24. Haas B, L Bonifait, K Vaillancourt, SJ Charette, M Gottschalk, D Grenier. DNase activity of Streptococcus suis: Characterization and possible roles in virulence. 5e Symposium du Centre de Recherche en Infectiologie Porcine, Québec (Canada), Mai 2012.
  25. Bonifait L, K Vaillancourt, D Grenier. The subtilisin-like protease of Streptococcus suis inactivates the antimicrobial peptide cathelicidin LL-37. 5e Symposium du Centre de Recherche en Infectiologie Porcine, Québec (Canada), Mai 2012.
  26. Bonifait L, SJ Charette, M Gottschalk, D Grenier. Mise en évidence de facteurs de virulence chez Streptococcus suis à l’aide du modèle hôte Dictyostelium discoideum. Congrès de bactériologie intégrative: symbiose et pathogenèse, Québec (Canada), Novembre 2011.
  27. Epifano F, S Genovese, M Curini, M Feldman, C Messier, D Grenier. 4-Idrossicordoina: attività anti-batterica, anti-fungina ed anti-infiammatoria. XI Congresso Nazionale Società Italiana di Fitochimica (SIF), Roma (Italy), Septembre 2011.
  28. Grenier D. Cranberry proanthocyanidins: Natural weapons against tissue destruction and bone resorption associated with periodontal diseases. Berry Health Benefits Symposium, Westlake Village (USA), Juillet 2011.
  29. Bedran TBL, D Grenier, LC Spolidorio, A Fontana, M Nogueira, M Correia, D Spolidorio. Comparative analysis between conventional PCR and qPCR for detection of periodontopathogens. International Association for Dental Research, San Diego (USA), Juillet 2011.
  30. Grenier D. Licorice and Aloe vera: Can they be used to prevent or treat oral diseases? Tom’s of Maine Symposium, Portland (USA), Juin 2011.
  31. Epifano F, S Genovese, M Feldman, D Grenier. Synthesis and anti-inflammatory properties of 4’-O-geranylisoliquiritigenin, active principle of Millettia spp. (Leguminosae) The International Conference on Natural Products, Castres (France), Mai 2011.
  32. Grenier D. Cranberry proanthocyanidins: Natural weapons against periodontal diseases. University « G. D’Annunzio », Chieti-Pescara (Italy), Mai 2011.
  33. Grenier D. Le xylitol: Un sucre aux multiples vertus, Éducation continue pour dentistes et hygiénistes dentaires, Québec (Canada), Mars 2011.

Prix et distinctions

Prix W.W. Wood, Excellence en enseignement dentaire, l’Association des Facultés dentaires du Canada, 2012


Autre

Membre régulier du Groupe de recherche en écologie buccale.